| Description : |
The protein encoded by this gene is specifically expressed in the inner ear, and is located at the interface between the apical surface of the inner ear sensory epithelia and their overlying acellular gels. It is prposed that this protein is involved in the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in this gene are associated with autosomal recessive deafness type 22 (DFNB22). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
126.8 kDa |
| AA Sequence : |
MSQEPTTYSLFLFLFLSHGVSSYTV PNSRQDLHPLLQNMAEEIIDGSYLN ALLDLIQFQSSHVWTDDLSHRVLAY LNSRNVAFTIPSLQAAVENHLEQRL HQPQKLLEDLRKTDAQQFRTAMKCL LEDKKDGLDLKDIIIDLGEIRERAL QSPGVNRSLFLITLERCFQMLNSLE CVEILGKVLRGSSGSFLQPDITERL PRDLREDAFKNLSAVFKDLYDKTSA HSQRALYSWMTGILQTSSNATDDSA SWVSAEHLWVLGRYMVHLSFEEITK ISPIEIGLFISYDNATKQLDMVYDI TPELAQAFLERISSSNFNMRNTSTI HRLGLLVCFYNDLELLDATVAQVLL YQMIKCSHLRGFQAGVQKLKAELLD IAMENQTLNETLGSLSDAVVGLTYS QLESLSPEAVHGAISTLNQVSGWAK SQVIILSAKYLAHEKVLSFYNVSQM GALLAGVSTQAFCSMKRKDISQVLR SAVSQYVSDLSPAQQQGILSKMVQA EDTAPGIVEIQGAFFKEVSLFDLRR QPGFNSTVLKDKELGRSQALFLYEL LLKTTRRPEELLSAGQLVKGVTCSH IDAMSTDFFLAHFQDFQNNFALLSP YQVNCLAWKYWEVSRLSMPPFLLAA LPARYLASVPASQCVPFLISLGKSW LDSLVLDSHKKTSVLRKVQQCLDDS IADEYTVDIMGNLLCHLPAAIIDRG ISPRAWATALHGLRDCPDLNPEQKA AVRLKLLGQYGLPQHWTAETTKDLG PFLVLFSGDELSSIATKFPEILLQA ASKMARTLPTKEFLWAVFQSVRNSS DKIPSYDPMPGCHGVVAPSSDDIFK LAEANACWALEDLRCMEEDTFIRTV ELLGAVQGFSRPQLMTLKEKAIQVW DMPSYWREHHIVSLGRIALALNESE LEQLDLSSIDTVASLSWQTEWTPGQ AESILQGYLDDSGYSIQDLKSFHLV GLGATLCAINITEIPLIKISEFRVV VARIGTLLCSTHVLAEFKRKAEVVF GDPTEWTSSVLQELGTIAAGLTKAA LRMLDKDLMPYFQPSAIKCLPDEIF KELSAEQIASLGPENAAAVTHAQRR RLSPLQLQSLQQALDGAKTHSWQDA PASAGPTRTSSSRSPAGALQSWGLW LGCPLLVLMAKLLWTRTRPLEQKLI SEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
