Recombinant Human OTUD5 Protein (G172-G351), His/Flag tagged

Species :	Human
Source :	E.coli
Tag :	Flag&His
Protein Length :	G172-G351
Description :	Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro). Controls neuroectodermal differentiation through cleaving 'Lys-48'-linked ubiquitin chains to counteract degradation of select chromatin regulators such as ARID1A, HDAC2 and HCF1.
Form :	Liquid
Endotoxin :	< 0.01 EU per μg of the protein
Purity :	90%
Stability :	Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
Storage :	Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Storage Buffer :	Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Shipping :	It is shipped out with blue ice.

Gene Name	OTUD5 OTU domain containing 5 [ Homo sapiens (human) ]
Official Symbol	OTUD5
Synonyms	DUBA
Gene ID	55593
mRNA Refseq	NM_017602
Protein Refseq	NP_060072
MIM	300713
UniProt ID	Q96G74