| Description : |
This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly(A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' exoribonuclease that is involved in the degradation of cytoplasmic mRNAs. Alternate splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
135 kDa |
| AA Sequence : |
MNFEGLDPGLAEYAPAMHSALDPVL DAHLNPNLLQNVELDPEGVALEALP VQESVHIMEGVYSELHSVVAEVGVP VSVSHFDLHEEMLWVGSHGGHATSF FGPALERYSSFQVNGSDDIRQIQSL ENGILFLTKNNLKYMARGGLIIFDY LLDENEDMHSLLLTDSSTLLVGGLQ NHILEIDLNTVQETQKYAVETPGVT IMRQTNRFFFCGHTSGKVSLRDLRT FKVEHEFDAFSGSLSDFDVHGNLLA ACGFSSRLTGLACDRFLKVYDLRMM RAITPLQVHVDPAFLRFIPTYTSRL AIISQSGQCQFCEPTGLANPADIFH VNPVGPLLMTFDVSASKQALAFGDS EGCVHLWTDSPEPSFNPYSRETEFA LPCLVDSLPPLDWSQDLLPLSLIPV PLTTDTLLSDWPAANSAPAPRRAPP VDAEILRTMKKVGFIGYAPNPRTRL RNQIPYRLKESDSEFDSFSQVTESP VGREEEPHLHMVSKKYRKVTIKYSK LGLEDFDFKHYNKTLFAGLEPHIPN AYCNCMIQVLYFLEPVRCLIQNHLC QKEFCLACELGFLFHMLDLSRGDPC QGNNFLRAFRTIPEASALGLILADS DEASGKGNLARLIQRWNRFILTQLH QDMQELEIPQAYRGAGGSSFCSSGD SVIGQLFSCEMENCSLCRCGSETVR ASSTLLFTLSYPDDKTGKNYDFAQV LKRSICLDQNTQAWCDTCEKYQPTI QTRNIRHLPDILVINCEVNSSKEAD FWRMQAEVAFKMAVKKHGGEISKNK EFALADWKELGSPEGVLVCPSIEEL KNVWLPFSIRMKMTKNKGLDVCNWT DGDEMQWGPARAEEEHGVYVYDLMA TVVHILDSRTGGSLVAHIKVGETYH QRKEGVTHQQWYLFNDFLIEPIDKH EAVQFDMNWKVPAILYYVKRNLNSR YNLNIKNPIEASVLLAEASLARKQR KTHTTFIPLMLNEMPQIGDLVGLDA EFVTLNEEEAELRSDGTKSTIKPSQ MSVARITCVRGQGPNEGIPFIDDYI STQEQVVDYLTQYSGIKPGDLDAKI SSKHLTTLKSTYLKLRFLIDIGVKF VGHGLQKDFRVINLMVPKDQVLDTV YLFHMPRKRMISLRFLAWYFLDLKI QGETHDSIEDARTALQLYRKYLELS KNGTEPESFHKVLKGLYEKGRKMDW KVPEPEGQTSPKNAAVFSSVLALTR TRPLEQKLISEEDLAANDILDYKDD DDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
