Recombinant Human PANK4, His-tagged

• Cat.No.: PANK4-28661TH
• Product Overview: Recombinant fragment, corresponding to amino acids 16-650 of Human PANK4 with an N terminal His tag. Predicted mwt: 72 kDa

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 16-650 a.a.
• Description: This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues.
• Conjugation: HIS
• Form: Lyophilised:Reconstitute with 108 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: LDKSITLPPDEIFRNLENAKRFAIDIGGSLTKLAYYSTVQ HKVAKVRSFDHSGKDTEREHEPPYEISVQEEITARLHF IKFENTYIEACLDFIKDHLVNTETKVIQATGGGAYKFKDL IEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQK DSDPEFRFQTNHPHIFPYLLVNIGSGVSIVKVETEDRF EWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSN VDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQEFS KEDMAKSLLHMISNDIGQLACLHARLHSLDRVYFGGFF IRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAF LKGAEQDNPNQYSWGENYAGSSGLMSASPELGPAQRAR SGTFDLLEMDRLERPLVDLPLLLDPPSYVPDTVDLTDD ALARKYWLTCFEEALDGVVKRAVASQPDSVDAAERAEKFR QKYWNKLQTLRQQPFAYGTLTVRSLLDTREHCLNEFNF PDPYSKVKQRENGVALRCFPGVVRSLDALGWEERQLAL VKGLLAGNVFDWGAKAVSAVLESDPYFGFEEAKRKLQERP WLVDSYSEWLQRLKGPPHKCALIFADNSGIDIILGVFP FVRELLLRGTEVILA

Gene Information

• Gene Name: PANK4 pantothenate kinase 4 [ Homo sapiens ]
• Official Symbol: PANK4
• Synonyms: PANK4; pantothenate kinase 4; FLJ10782
• Gene ID: 55229
• mRNA Refseq: NM_018216
• Protein Refseq: NP_060686
• MIM: 606162
• Uniprot ID: Q9NVE7
• Chromosome Location: 1p36.32
• Pathway: Coenzyme A biosynthesis, organism-specific biosystem; Coenzyme A biosynthesis, pantothenate => CoA, organism-specific biosystem; Coenzyme A biosynthesis, pantothenate => CoA, conserved biosystem
• Function: ATP binding; nucleotide binding; pantothenate kinase activity; transferase activity