Recombinant Human PBRM1 Protein, His-tagged

• Cat.No.: PBRM1-761H
• Product Overview: Recombinant Human PBRM1(Met1~Ala306) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma.
• Source: E. coli
• Species: Human
• Tag: His
• Form: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Molecular Mass: 65kDa
• Protein length: Met1~Ala306
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 92%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: PBRM1 polybromo 1 [ Homo sapiens ]
• Official Symbol: PBRM1
• Synonyms: PBRM1; polybromo 1; protein polybromo-1; BAF180; PB1; polybromo-1D; BRG1-associated factor 180; MGC156155; MGC156156
• Gene ID: 55193
• mRNA Refseq: NM_018313
• Protein Refseq: NP_060783
• MIM: 606083
• UniProt ID: Q86U86