| Description : |
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This family member contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein is a cadherin-related neuronal receptor thought to function in the establishment of specific cell-cell connections in the brain. This gene plays a role in inhibiting cancer cell motility and cell migration. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Source : |
HEK293 cells |
| Species : |
Human |
| Tag : |
Fc |
| Form : |
Lyophilized from a 0.2 µM filtered solution of PBS, pH 7.4 |
| Molecular Mass : |
102.4kD |
| AA Sequence : |
QLHYTVQEEQEHGTFVGNIAEDLGL DITKLSARGFQTVPNSRTPYLDLNL ETGVLYVNEKIDREQICKQSPSCVL HLEVFLENPLELFQVEIEVLDINDN PPSFPEPDLTVEISESATPGTRFPL ESAFDPDVGTNSLRDYEITPNSYFS LDVQTQGDGNRFAELVLEKPLDREQ QAVHRYVLTAVDGGGGGGVGEGGGG GGGAGLPPQQQRTGTALLTIRVLDS NDNVPAFDQPVYTVSLPENSPPGTL VIQLNATDPDEGQNGEVVYSFSSHI SPRARELFGLSPRTGRLEVSGELDY EESPVYQVYVQAKDLGPNAVPAHCK VLVRVLDANDNAPEISFSTVKEAVS EGAAPGTVVALFSVTDRDSEENGQV QCELLGDVPFRPKSSFKNYYTIVTE APLDREAGDSYTLTVVARDRGEPAL STSKSIQVQVSDVNDNAPRFSQPVY DVYVTENNVPGAYIYAVSATDRDEG ANAQLAYSILECQIQGMSVFTYVSI NSENGYLYALRSFDYEQLKDFSFQV EARDAGSPQALAGNATVNILIVDQN DNAPAIVAPLPGRNGTPAREVLPRS AEPGYLLTRVAAVDADDGENARLTY SIVRGNEMNLFRMDWRTGELRTARR VPAKRDPQRPYELVIEVRDHGQPPL SSTATLVVQLVDGAVEPQGGGGSGG GGSGEHQRPSRSGGGETSLDLTVDD IEGRMDEPKSCDKTHTCPPCPAPEL LGGPSVFLFPPKPKDTLMISRTPEV TCVVVDVSHEDPEVKFNWYVDGVEV HNAKTKPREEQYNSTYRVVSVLTVL HQDWLNGKEYKCKVSNKALPAPIEK TISKAKGQPREPQVYTLPPSREEMT KNQVSLTCLVKGFYPSDIAVEWESN GQPENNYKTTPPVLDSDGSFFLYSK LTVDKSRWQQGNVFSCSVMHEALHN HYTQKSLSLSPGK |
| Endotoxin : |
Endotoxin level is <0.1 ng/µg of protein (<1EU/µg). |
| Purity : |
>95% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration : |
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
