Recombinant Human PDCD1LG2 protein, Avi & His-tagged, Biotinylated
Cat.No. : | PDCD1LG2-1281H |
Product Overview : | Biotinylated Human PD-L2 (recommended for biopanning) is expressed from human 293 cells (HEK293). It contains AA Leu 20 - Pro 219 (Accession # AAI13679). Biotinylation of this product is performed using Avitag technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin. The biotin to protein ratio is 0.5-1 as determined by the HABA assay. |
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Description : | Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
Source : | HEK293 |
Species : | Human |
Tag : | Avi & His |
Predicted N Terminal : | Leu 20 |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 25.2 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Leu 20 - Pro 219 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. No activity loss is observed after storage at: 4-8°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | PDCD1LG2 programmed cell death 1 ligand 2 [ Homo sapiens (human) ] |
Official Symbol : | PDCD1LG2 |
Synonyms : | B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2; B7 dendritic cell molecule; B7-DC; PD-1-ligand 2; PDCD1 ligand 2; butyrophilin B7-DC; programmed death ligand 2; programmed cell death 1 ligand 2 |
Gene ID : | 80380 |
mRNA Refseq : | NM_025239.3 |
Protein Refseq : | NP_079515.2 |
UniProt ID : | Q9BQ51 |
Products Types
◆ Recombinant Protein | ||
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PDCD1LG2-720M | Recombinant Mouse PDCD1LG2 Protein, IgG2a Fc-tagged | +Inquiry |
Pdcd1lg2-4732M | Recombinant Mouse Pdcd1lg2 Protein, Myc/DDK-tagged | +Inquiry |
PDCD1LG2-11H | Recombinant Human PDCD1LG2 Protein, C-6His-Avi tagged, Biotinylated | +Inquiry |
◆ Lysates | ||
PDCD1LG2-2721HCL | Recombinant Human PDCD1LG2 cell lysate | +Inquiry |
PDCD1LG2-951CCL | Recombinant Cynomolgus PDCD1LG2 cell lysate | +Inquiry |
PDCD1LG2-1738MCL | Recombinant Mouse PDCD1LG2 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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