Recombinant Human PDE1C Protein, His/GST-tagged

Cat.No. : PDE1C-03H
Product Overview : Recombinant human PDE1C protein (1-634) with a N-teminus His/GST-tag was expressed in insect cells.
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Description : This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta.
Source : Insect cell
Species : Human
Tag : His/GST
Form : Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10% glycerol, 3 mM DTT
Molecular Mass : 100 kDa
Protein length : 1-634
Endotoxin : <1.0 EU/μg of the protein as determined by the LAL method
Purity : ≥85 % as determined by SDS-PAGE
Stability : ≥ 1 year
Storage : Store at -80 centigrade
SDS-PAGE: Lane 1: MW Markers, Lane 2: PDE1C1, SDS-PAGE Analysis of PDE1C1. This protein has a calculated molecular weight of 100 kDa. It has an apparent molecular weight of approximately 97 kDa by SDS-PAGE under reducing condions.
Gene Name : PDE1C phosphodiesterase 1C [ Homo sapiens (human) ]
Official Symbol : PDE1C
Synonyms : PDE1C; phosphodiesterase 1C; Hcam3; DFNA74; hCam-3; cam-PDE 1C; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; 3',5'-cyclic-AMP phosphodiesterase; 3',5'-cyclic-GMP phosphodiesterase; Human 3',5' cyclic nucleotide phosphodiesterase (HSPDE1C1A); phosphodiesterase 1C, calmodulin-dependent 70kDa
Gene ID : 5137
mRNA Refseq : NM_001191056
Protein Refseq : NP_001177985
MIM : 602987
UniProt ID : Q14123

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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