Recombinant Human PDIA4 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | PDIA4-3929H |
Product Overview : | PDIA4 MS Standard C13 and N15-labeled recombinant protein (NP_004902) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
- Download
Description : | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, three catalytically active thioredoxin (TRX) domains, two TRX-like domains and a C-terminal ER-retention sequence. This protein, when bound to cyclophilin B, enhances the rate of immunoglobulin G intermolecular disulfide bonding and antibody assembly. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc&DDK |
Molecular Mass : | 72.9 kDa |
AA Sequence : | MRPRKAFLLLLLLGLVQLLAVAGAE GPDEDSSNRENAIEDEEEEEEEDDD EEEDDLEVKEENGVLVLNDANFDNF VADKDTVLLEFYAPWCGHCKQFAPE YEKIANILKDKDPPIPVAKIDATSA SVLASRFDVSGYPTIKILKKGQAVD YEGSRTQEEIVAKVREVSQPDWTPP PEVTLVLTKENFDEVVNDADIILVE FYAPWCGHCKKLAPEYEKAAKELSK RSPPIPLAKVDATAETDLAKRFDVS GYPTLKIFRKGRPYDYNGPREKYGI VDYMIEQSGPPSKEILTLKQVQEFL KDGDDVIIIGVFKGESDPAYQQYQD AANNLREDYKFHHTFSTEIAKFLKV SQGQLVVMQPEKFQSKYEPRSHMMD VQGSTQDSAIKDFVLKYALPLVGHR KVSNDAKRYTRRPLVVVYYSVDFSF DYRAATQFWRSKVLEVAKDFPEYTF AIADEEDYAGEVKDLGLSESGEDVN AAILDESGKKFAMEPEEFDSDTLRE FVTAFKKGKLKPVIKSQPVPKNNKG PVKVVVGKTFDSIVMDPKKDVLIEF YAPWCGHCKQLEPVYNSLAKKYKGQ KGLVIAKMDATANDVPSDRYKVEGF PTIYFAPSGDKKNPVKFEGGDRDLE HLSKFIEEHATKLSRTKEELTRTRP LEQKLISEEDLAANDILDYKDDDDK V |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | PDIA4 protein disulfide isomerase family A member 4 [ Homo sapiens (human) ] |
Official Symbol : | PDIA4 |
Synonyms : | PDIA4; protein disulfide isomerase family A, member 4; protein disulfide isomerase associated 4; protein disulfide-isomerase A4; ERP70; ERP72; ER protein 70; ER protein 72; protein disulfide isomerase-associated 4; endoplasmic reticulum resident protein 70; endoplasmic reticulum resident protein 72; protein disulfide isomerase related protein (calcium-binding protein, intestinal-related); ERp-72; |
Gene ID : | 9601 |
mRNA Refseq : | NM_004911 |
Protein Refseq : | NP_004902 |
UniProt ID : | P13667 |
Products Types
◆ Recombinant Protein | ||
Pdia4-740M | Recombinant Mouse Pdia4 Protein, MYC/DDK-tagged | +Inquiry |
PDIA4-4005R | Recombinant Rat PDIA4 Protein, His (Fc)-Avi-tagged | +Inquiry |
PDIA4-6603M | Recombinant Mouse PDIA4 Protein, His (Fc)-Avi-tagged | +Inquiry |
PDIA4-1513C | Recombinant Chicken PDIA4 | +Inquiry |
PDIA4-5355H | Recombinant Human PDIA4 Protein (Phe505-Thr636), N-His tagged | +Inquiry |
◆ Lysates | ||
PDIA4-1285HCL | Recombinant Human PDIA4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewGreat performance in ELISA.
The PDIA4 protein demonstrates exceptional quality, making it an ideal candidate to fulfill my experimental requirements.
Its purity and functionality ensure precise and reproducible results, enabling me to achieve my research objectives with confidence.
Q&As (5)
Ask a questionYes, there are immunoassays and other diagnostic tests available to measure PDIA4 protein levels in clinical samples.
PDIA4 has been shown to play a role in the regulation of vascular function and endothelial cell survival, making it relevant to the pathophysiology of cardiovascular diseases.
Yes, research suggests that PDIA4 may play a role in insulin resistance and pancreatic beta-cell function, making it a potential target for therapeutic intervention in diabetes.
PDIA4 has been shown to be involved in the misfolding and aggregation of proteins associated with Alzheimer's disease, suggesting a potential role in disease progression.
Research has indicated that PDIA4 may be involved in the pathogenesis of autoimmune diseases, making it a potential therapeutic target for these conditions.
Ask a Question for All PDIA4 Products
Required fields are marked with *
My Review for All PDIA4 Products
Required fields are marked with *
Inquiry Basket