Description : |
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
98.8 kDa |
AA Sequence : |
MTELKAKGPRAPHVAGGPPSPEVGS PLLCRPAAGPFPGSQTSDTLXEVSA IPISLDGLLFPRPCQGQDPSDEKTQ DQQSLSDVEGAYSRAEATRGAGGSS SSPPEKDSGLLDSVLDTLLAPSGPG QSQPSPPACEVTSSWCLFGPELPED PPAAPATQRVLSPLMSRSGCKVGDS SGTAAAHKVLPRGLSPARQLLLPAS ESPHWSGAPVKPSPQAAAVEVEEED GSESEESAGPLLKGKPRALGGAAAG GGAAAVPPGAAAGGVALVPKEDSRF SAPRVALVEQDAPMAPGRSPLATTV MDFIHVPILPLNHALLAARTRQLLE DESYDGGAGAASAFAPPRSSPCASS TPVAVGDFPDCAYPPDAEPKDDAYP LYSDFQPPALKIKEEEEXAEASARS PRSYLVAGANPAAFPDFPLGPPPPL PPRATPSRPGEAAVTAAPASASVSS ASSSGSTLECILYKAEGAPPQQGPF APPPCKAPGASGCLLPRDGLPSTSA SAAAAGAAPALYPALGLNGLPQLGY QAAVLKEGLPQVYPPYLNYLRPDSE ASQSPQYSFESLPQKICLICGDEAS GCHYGVLTCGSCKVFFKRAMEGQHN YLCAGRNDCIVDKIRRKNCPACRLR KCCQAGMVLGGRKFKKFNKVRVVRA LDAVALPQPVGVPNESQALSQRFTF SPGQDIQLIPPLINLLMSIEPDVIY AGHDNTKPDTSSSLLTSLNQLGERQ LLSVVKWSKSLPGFRNLHIDDQITL IQYSWMSLMVFGLGWRSYKHVSGQM LYFAPDLILNEQRMKESSFYSLCLT MWQIPQEFVKLQVSQEEFLCMKVLL LLNTIPLEGLRSQTQFEEMRSSYIR ELIKAIGLRQKGVVSSSQRFYQLTK LLDNLHDLVKQLHLYCLNTFIQSRA LSVEFPEMMSEVIAAQLPKILAGMV KPLLFHKKTRRLEQKLISEEDLAAN DILDYKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |