Recombinant Human PHYH Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human PHYH Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : PHYH-3396H
Product Overview : PHYH MS Standard C13 and N15-labeled recombinant protein (NP_006205) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene is a member of the PhyH family and encodes a peroxisomal protein that is involved in the alpha-oxidation of 3-methyl branched fatty acids. Specifically, this protein converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Mutations in this gene have been associated with Refsum disease (RD) and deficient protein activity has been associated with Zellweger syndrome and rhizomelic chondrodysplasia punctata. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 38.5 kDa
AA Sequence : MEQLRAAARL QIVLGHLGRP SAGAVVAHPT SGTISSASFH PQQFQYTLDN NVLTLEQRKF YEENGFLVIK NLVPDADIQR FRNEFEKICR KEVKPLGLTV MRDVTISKSE YAPSEKMITK VQDFQEDKEL FRYCTLPEIL KYVECFTGPN IMAMHTMLIN KPPDSGKKTS RHPLHQDLHY FPFRPSDLIV CAWTAMEHIS RNNGCLVVLP GTHKGSLKPH DYPKWEGGVN KMFHGIQDYE ENKARVHLVM EKGDTVFFHP LLIHGSGQNK TQGFRKAISC HFASADCHYI DVKGTSQENI EKEVVGIAHK FFGAENSVNL KDIWMFRARL VKGERTNLTR TRPLEQKLIS EEDLAANDIL DYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : PHYH phytanoyl-CoA 2-hydroxylase [ Homo sapiens (human) ]
Official Symbol : PHYH
Synonyms : PHYH; phytanoyl-CoA 2-hydroxylase; phytanoyl CoA hydroxylase, phytanoyl CoA hydroxylase (Refsum disease); phytanoyl-CoA dioxygenase, peroxisomal; PAHX; PHYH1; phytanoyl CoA dioxygenase; RD; Refsum disease; phytanic acid oxidase; phytanoil-CoA alpha hydroxylase; phytanoyl-CoA alpha-hydroxylase; phytanoyl-CoA 2 oxoglutarate dioxygenase; LN1; LNAP1;
Gene ID : 5264
mRNA Refseq : NM_006214
Protein Refseq : NP_006205
MIM : 602026
UniProt ID : O14832

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