Recombinant Human PKN1 protein, His & T7-tagged
Cat.No. : | PKN1-2709H |
Product Overview : | Recombinant Human PKN1 aa. (Phe615~Phe874 (Accession # Q16512)) fused with N-terminal His & T7 tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
Source : | E. coli |
Species : | Human |
Tag : | His & T7 |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 32.9kDa |
Protein length : | Phe615~Phe874 (Accession # Q16512) |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 5.9. |
Applications : | SDS-PAGE; WB; ELISA; IP |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name : | PKN1 protein kinase N1 [ Homo sapiens (human) ] |
Official Symbol : | PKN1 |
Synonyms : | DBK; PKN; PAK1; PRK1; PAK-1; PRKCL1; PKN-ALPHA; protease-activated kinase 1; protein kinase C-like 1; protein kinase C-like PKN; protein kinase C-related kinase 1; protein kinase PKN-alpha; serine-threonine kinase N; serine/threonine protein kinase N; serine/threonine-protein kinase N1 |
Gene ID : | 5585 |
mRNA Refseq : | NM_002741.3 |
Protein Refseq : | NP_002732.3 |
UniProt ID : | Q16512 |
Products Types
◆ Recombinant Protein | ||
PKN1-4142R | Recombinant Rat PKN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Pkn1-4890M | Recombinant Mouse Pkn1 Protein, Myc/DDK-tagged | +Inquiry |
PKN1-6787M | Recombinant Mouse PKN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PKN1-4433H | Recombinant Human PKN1 protein, His-tagged | +Inquiry |
PKN1-4986H | Recombinant Human PKN1 Protein (Val725-Phe874), N-His tagged | +Inquiry |
◆ Lysates | ||
PKN1-1363HCL | Recombinant Human PKN1 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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