Recombinant Human PLA2G12B Protein, MYC/DDK-tagged

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Recombinant Human PLA2G12B Protein, MYC/DDK-tagged

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Cat.No. : PLA2G12B-1880H
Product Overview : Recombinant human PLA2G12B protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293
Description : The protein encoded by this gene belongs to the phospholipase A2 (PLA2) group of enzymes, which function in glycolipid hydrolysis with the release of free fatty acids and lysophospholipids. This family member has altered phospholipid-binding properties and is catalytically inactive. The protein is secreted, and together with microsomal triglyceride transfer protein, it functions to regulate HNF4alpha-induced hepatitis C virus infectivity. The expression of this gene is down-regulated in various tumors, suggesting that it may function as a negative regulator of tumor progression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 21.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : PLA2G12B phospholipase A2, group XIIB [ Homo sapiens ]
Official Symbol : PLA2G12B
Synonyms : FKSG71; GXIIB; GXIIIsPLA2; PLA2G13; sPLA2-GXIIB
Gene ID : 84647
mRNA Refseq : NM_032562
Protein Refseq : NP_115951
MIM : 611653
UniProt ID : Q9BX93

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