Recombinant Human PLTP Protein (18-493 aa), GST-tagged

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Recombinant Human PLTP Protein (18-493 aa), GST-tagged

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Cat.No. : PLTP-728H
Product Overview : Recombinant Human PLTP Protein (18-493 aa) is produced by E. coli expression system. This protein is fused with a GST tag at the N-terminal. Research Area: Transport. Protein Description: Full Length of Mature Protein.
Description : Facilitates the transfer of a spectrum of different lipid molecules, including diacylglycerol, phosphatidic acid, sphingomyelin, phosphatidylcholine, phosphatidylglycerol, cerebroside and phosphatidyl ethanolamine. Essential for the transfer of excess surface lipids from triglyceride-rich lipoproteins to HDL, thereby facilitating the formation of smaller lipoprotein rnants, contributing to the formation of LDL, and assisting in the maturation of HDL particles. PLTP also plays a key role in the uptake of cholesterol from peripheral cells and tissues that is subsequently transported to the liver for degradation and excretion. Two distinct forms of PLTP exist in plasma: an active form that can transfer PC from phospholipid vesicles to high-density lipoproteins (HDL), and an inactive form that lacks this capability.
Source : E. coli
Species : Human
Tag : GST
Form : Tris-based buffer, 50% glycerol
Molecular Mass : 80.1 kDa
Protein length : 18-493 aa
AA Sequence : EFPGCKIRVT SKALELVKQE GLRFLEQELE TITIPDLRGK EGHFYYNISE VKVTELQLTS SELDFQPQQE LMLQITNASL GLRFRRQLLY WFFYDGGYIN ASAEGVSIRT GLELSRDPAG RMKVSNVSCQ ASVSRMHAAF GGTFKKVYDF LSTFITSGMR FLLNQQICPV LYHAGTVLLN SLLDTVPVRS SVDELVGIDY SLMKDPVAST SNLDMDFRGA FFPLTERNWS LPNRAVEPQL QEEERMVYVA FSEFFFDSAM ESYFRAGALQ LLLVGDKVPH DLDMLLRATY FGSIVLLSPA VIDSPLKLEL RVLAPPRCTI KPSGTTISVT ASVTIALVPP DQPEVQLSSM TMDARLSAKM ALRGKALRTQ LDLRRFRIYS NHSALESLAL IPLQAPLKTM LQIGVMPMLN ERTWRGVQIP LPEGINFVHE VVTNHAGFLT IGADLHFAKG LREVIEKNRP ADVRASTAPT PSTAAV
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with concentration instruction is sent along with the products.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : PLTP phospholipid transfer protein [ Homo sapiens ]
Official Symbol : PLTP
Synonyms : PLTP; BPIFE; lipid transfer protein II; HDLCQ9;
Gene ID : 5360
mRNA Refseq : NM_001242920
Protein Refseq : NP_001229849
UniProt ID : P55058
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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