Recombinant Human PLVAP Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PLVAP-2618H
• Product Overview: PLVAP MS Standard C13 and N15-labeled recombinant protein (NP_112600) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Endothelial cell-specific membrane protein involved in the formation of the diaphragms that bridge endothelial fenestrae. It is also required for the formation of stomata of caveolae and transendothelial channels. Functions in microvascular permeability, endothelial fenestrae contributing to the passage of water and solutes and regulating transcellular versus paracellular flow in different organs. Plays a specific role in embryonic development.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 50.4 kDa
• AA Sequence: MGLAMEHGGSYARAGGSSRGCWYYL RYFFLFVSLIQFLIILGLVLFMVYG NVHVSTESNLQATERRAEGLYSQLL GLTASQSNLTKELNFTTRAKDAIMQ MWLNARRDLDRINASFRQCQGDRVI YTNNQRYMAAIILSEKQCRDQFKDM NKSCDALLFMLNQKVKTLEVEIAKE KTICTKDKESVLLNKRVAEEQLVEC VKTRELQHQERQLAKEQLQKVQALC LPLDKDKFEMDLRNLWRDSIIPRSL DNLGYNLYHPLGSELASIRRACDHM PSLMSSKVEELARSLRADIERVARE NSDLQRQKLEAQQGLRASQEAKQKV EKEAQAREAKLQAECSRQTQLALEE KAVLRKERDNLAKELEEKKREAEQL RMELAIRNSALDTCIKTKSQPMMPV SRPMGPVPNPQPIDPASLEEFKRKI LESQRPPAGIPVAPSSGSGPTRTRR LEQKLISEEDLAANDILDYKDDDDK V
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PLVAP plasmalemma vesicle associated protein [ Homo sapiens (human) ]
• Official Symbol: PLVAP
• Synonyms: PLVAP; plasmalemma vesicle associated protein; plasmalemma vesicle-associated protein; FELS; fenestrated endothelial linked structure protein; PV 1 protein; gp68; PV 1; PV1; plasmalemma vesicle protein 1; fenestrated endothelial-linked structure protein; fenestrated-endothelial linked structure protein; PV-1 protein; PV-1
• Gene ID: 83483
• mRNA Refseq: NM_031310
• Protein Refseq: NP_112600
• MIM: 607647
• UniProt ID: Q9BX97