Recombinant Human PMEPA1 Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: PMEPA1-144H
• Product Overview: PMEPA1 MS Standard C13 and N15-labeled recombinant protein (NP_954639) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 26 kDa
• AA Sequence: MMVMVVVITCLLSHYKLSARSFISR HSQGRRREDALSSEGCLWPSESTVS GNGIPEPQVYAPPRPTDRLAVPPFA QRERFHRFQPTYPYLQHEIDLPPTI SLSDGEEPPPYQGPCTLQLRDPEQQ LELNRESVRAPPNRTIFDSDLMDSA RLGGPCPPSSNSGISATCYGSGGRM EGPPPTYSEVIGHYPGSSFQHQQSS GPPSLLEGTRLHHTHIAPLESAAIW SKEKDKQKGHPLTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PMEPA1 prostate transmembrane protein, androgen induced 1 [ Homo sapiens (human) ]
• Official Symbol: PMEPA1
• Synonyms: PMEPA1; prostate transmembrane protein, androgen induced 1; STAG1; TMEPAI; protein TMEPAI; solid tumor-associated 1 protein; transmembrane, prostate androgen induced RNA
• Gene ID: 56937
• mRNA Refseq: NM_199170
• Protein Refseq: NP_954639
• MIM: 606564
• UniProt ID: Q969W9