Recombinant Human PNPLA6 Protein, MYC/DDK-tagged

• Cat.No.: PNPLA6-2408H
• Product Overview: Recombinant Human PNPLA6 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 150.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PNPLA6 patatin-like phospholipase domain containing 6 [ Homo sapiens ]
• Official Symbol: PNPLA6
• Synonyms: BNHS; iPLA2delta; LNMS; NTE; NTEMND; OMCS; SPG39; sws
• Gene ID: 10908
• mRNA Refseq: NM_001166111
• Protein Refseq: NP_001159583
• MIM: 603197
• UniProt ID: Q8IY17