Recombinant Human POLD4, His-tagged
Cat.No. : | POLD4-2282H |
Product Overview : | Recombinant human POLD4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | POLD4 is the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3" to 5" exonuclease activity and plays a critical role in DNA replication and repair. The protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% glycerol, 2mM DTT |
Molecular Mass : | 14.8 kDa |
Protein length : | 130aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMGRKRLI TDSYPVVKRR EGPAGHSKGE LAPELGEEPQ PRDEEEAELE LLRQFDLAWQ YGPCTGITRL QRWCRAKQMG LEPPPEVWQV LKTHPGDPRF QCSLWHLYPL |
Purity : | >90% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25 mg/ml |
Gene Name : | POLD4 polymerase (DNA-directed), delta 4 [ Homo sapiens ] |
Official Symbol : | POLD4 |
Synonyms : | POLD4; polymerase (DNA-directed), delta 4; DNA polymerase delta subunit 4; DNA polymerase delta smallest subunit p12; p12; POLDS; |
Gene ID : | 57804 |
mRNA Refseq : | NM_001256870 |
Protein Refseq : | NP_001243799 |
MIM : | 611525 |
UniProt ID : | Q9HCU8 |
Chromosome Location : | 11q13 |
Pathway : | Base Excision Repair, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; DNA Repair, organism-specific biosystem; |
Function : | DNA-directed DNA polymerase activity; nucleotidyltransferase activity; protein binding; transferase activity; |
Products Types
◆ Recombinant Protein | ||
Pold4-4984M | Recombinant Mouse Pold4 Protein, Myc/DDK-tagged | +Inquiry |
POLD4-3323R | Recombinant Rhesus Macaque POLD4 Protein, His (Fc)-Avi-tagged | +Inquiry |
POLD4-3505R | Recombinant Rhesus monkey POLD4 Protein, His-tagged | +Inquiry |
POLD4-301200H | Recombinant Human POLD4 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
POLD4-3051HCL | Recombinant Human POLD4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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