Recombinant Human POLE3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: POLE3-4950H
• Product Overview: POLE3 MS Standard C13 and N15-labeled recombinant protein (NP_059139) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.
• Molecular Mass: 16.9 kDa
• AA Sequence: MAERPEDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLNASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKTDSEEQDKSRDEDNDEDEERLEEEEQNEEEEVDNTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: POLE3 DNA polymerase epsilon 3, accessory subunit [ Homo sapiens (human) ]
• Official Symbol: POLE3
• Synonyms: POLE3; polymerase (DNA directed), epsilon 3 (p17 subunit); DNA polymerase epsilon subunit 3; arsenic transactivated protein; CHARAC17; CHRAC17; chromatin accessibility complex 17; DNA polymerase epsilon p17 subunit; histone fold protein CHRAC17; p17; Ybl1; asTP; CHRAC-17; huCHRAC17; DNA polymerase II subunit 3; arsenic-transactivated protein; DNA polymerase epsilon subunit p17; chromatin accessibility complex 17 kDa protein; YBL1
• Gene ID: 54107
• mRNA Refseq: NM_017443
• Protein Refseq: NP_059139
• MIM: 607267
• UniProt ID: Q9NRF9