Recombinant Human POLQ Protein (C terminal Domain, 1792-2590)

• Cat.No.: POLQ-27H
• Product Overview: Recombinant Human POLQ Protein (C terminal Domain, 1792-2590) without tag was expressed in E. coli. The C-terminal domain of Polq is located at the end of the enzyme's protein chain and is involved in various functions related to DNA repair. It contains specific motifs and regions that interact with other proteins and DNA molecules to facilitate repair processes.

Specification

• Description: The Pol Theta C-terminal domain refers to a specific region found in the DNA polymerase theta enzyme (Polq). Polq is a specialized DNA polymerase that plays a role in DNA repair processes, particularly in the repair of double-stranded DNA breaks.
• Source: E. coli
• Species: Human
• Molecular Mass: 90.97 kDa
• Protein Length: 1792-2590
• Purity: > 98% by SDS-PAGE
• Usage: DNA polymerase activity assay, Inhibitor screening for drug discovery, DNA repair mechanisms study
• Storage: Stable for 12 months at -80 centigrade, Avoid freeze/thaw cycles
• Storage Buffer: 40 mM Tris pH 8.0, 150 mM KCl, 150 mM ammonium acetate, 10% glycerol, 1 mM TCEP, 1 mM PMSF, 1 mM Benzamidine

Gene Information

• Gene Name: POLQ polymerase (DNA directed), theta [ Homo sapiens (human) ]
• Official Symbol: POLQ
• Synonyms: POLQ; polymerase (DNA directed), theta; DNA polymerase theta; POLH; DNA polymerase eta; PRO0327; DKFZp781A0112
• Gene ID: 10721
• mRNA Refseq: NM_199420
• Protein Refseq: NP_955452
• MIM: 604419
• UniProt ID: O75417