Recombinant Human POMGNT1 Protein, His-tagged

• Cat.No.: POMGNT1-237H
• Product Overview: Recombinant Human POMGNT1 fused with His tag at C-terminal was expressed in HEK293 cells.

Specification

• Description: This gene encodes a type II transmembrane protein that resides in the Golgi apparatus. It participates in O-mannosyl glycosylation and is specific for alpha linked terminal mannose. Mutations in this gene may be associated with muscle-eye-brain disease and several congenital muscular dystrophies. Alternatively spliced transcript variants that encode different protein isoforms have been described.
• Source: HEK293 cells
• Species: Human
• Tag: His
• Form: Supplied as a 0.2 µM filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 8.5
• Molecular Mass: 69.3kD
• AA Sequence: LDTRRAISEANEDPEPEQDYDEALG RLEPPRRRGSGPRRVLDVEVYSSRS KVYVAVDGTTVLEDEAREQGRGIHV IVLNQATGHVMAKRVFDTYSPHEDE AMVLFLNMVAPGRVLICTVKDEGSF HLKDTAKALLRSLGSQAGPALGWRD TWAFVGRKGGPVFGEKHSKSPALSS WGDPVLLKTDVPLSSAVEAECHWAD TELNRRRRRFCSKVEGYGSVCSCKD PTPIEFSPDPLPDNKVLNVPVAVIA GNRPNYLYRMLRSLLSAQGVSPQMI TVFIDGYYEEPMDVVALFGLRGIQH TPISIKNARVSQHYKASLTATFNLF PEAKFAVVLEEDLDIAVDFFSFLSQ SIHLLEEDDSLYCISAWNDQGYEHT AEDPALLYRVETMPGLGWVLRRSLY KEELEPKWPTPEKLWDWDMWMRMPE QRRGRECIIPDVSRSYHFGIVGLNM NGYFHEAYFKKHKFNTVPGVQLRNV DSLKKEAYEVEVHRLLSEAEVLDHS KNPCEDSFLPDTEGHTYVAFIRMEK DDDFTTWTQLAKCLHIWDLDVRGNH RGLWRLFRKKNHFLVVGVPASPYSV KKPPSVTPIFLEPPPKEEGAPGAPE QTVDHHHHHH
• Endotoxin: Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining

Gene Information

• Gene Name: POMGNT1 protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase [ Homo sapiens ]
• Official Symbol: POMGNT1
• Synonyms: POMGNT1; protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase; protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1; FLJ20277; MGAT1.2; protein O mannose beta 1; 2 N acetylglucosaminyltransferase; UDP-GlcNAc:alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.2; MEB; GNTI.2; MDDGA3; MDDGB3; MDDGC3; GnT I.2; gnT-I.2; DKFZp761B182
• Gene ID: 55624
• mRNA Refseq: NM_001243766
• Protein Refseq: NP_001230695
• MIM: 606822
• UniProt ID: Q8WZA1