Recombinant Human potassium channel tetramerization domain containing 4, His-tagged

• Cat.No.: KCTD4-339H
• Product Overview: KCTD4, 1-259aa, Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-259 a.a.
• Description: KCTD4 has an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KCTD4 is a 259 amino acid protein that contains one BTB domain, suggesting a possible role as a transcriptional regulator. Recombinant human KCTD4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 40% glycerol, 1mM DTT
• Molecular Mass: 32.4kDa (282aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMERKINR REKEKEYEGK HNSLEDTDQG KNCKSTLMTL NVGGYLYITQ KQTLTKYPDT FLEGIVNGKI LCPFDADGHY FIDRDGLLFR HVLNFLRNGE LLLPEGFREN QLLAQEAEFF QLKGLAEEVK SRWEKEQLTP RETTFLEITD NHDRSQGLRI FCNAPDFISK IKSRIVLVSK SRLDGFPEEF SISSNIIQFK YFIKSENGTR LVLKEDNTFV CTLETLKFEA IMMALKCGFR LLTSLDCSKG SIVHSDALHF IK
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: KCTD4 potassium channel tetramerisation domain containing 4 [ Homo sapiens ]
• Official Symbol: KCTD4
• Synonyms: KCTD4; potassium channel tetramerisation domain containing 4; BTB/POZ domain-containing protein KCTD4; bA321C24.3
• Gene ID: 386618
• mRNA Refseq: NM_198404
• Protein Refseq: NP_940686
• UniProt ID: Q8WVF5
• Chromosome Location: 13q14.12-q14.13
• Function: voltage-gated potassium channel activity