Recombinant Human PPIA protein, His-tagged

• Cat.No.: PPIA-1140H
• Product Overview: Recombinant Human PPIA protein(P62937)(Met1-Glu165), fused with His tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized from sterile 50mM Tris, 150mM NaCl, 20% glycerol, pH 7.7Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Molecular Mass: The recombinant human PPIA consisting of 175 amino acids and has a calculated molecular mass of 19.4 kDa as estimated in SDS-PAGE under reducing conditions.
• Protein Length: Met1-Glu165
• Purity: > 97 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: PPIA peptidylprolyl isomerase A (cyclophilin A) [ Homo sapiens ]
• Official Symbol: PPIA
• Synonyms: PPIA; peptidylprolyl isomerase A (cyclophilin A); peptidyl-prolyl cis-trans isomerase A; CYPA; PPIase A; rotamase A; cyclophilin; T cell cyclophilin; cyclosporin A-binding protein; CYPH; MGC12404; MGC23397; MGC117158
• Gene ID: 5478
• mRNA Refseq: NM_021130
• Protein Refseq: NP_066953
• MIM: 123840
• UniProt ID: P62937

Reviews

03/04/2022

The PPIA protein's robustness and stability have contributed significantly to the success of my experiments, enabling precise and reproducible measurements.

05/31/2020

I highly recommend the PPIA protein for a wide range of research applications.

06/16/2019

Its exceptional performance, in combination with its clear and distinct protein bands, make it an absolute must-have for researchers looking to achieve accurate and reliable results in their experiments.

Q&As

Can PPIA be used as a therapeutic target for infectious diseases?

PPIA has been studied in the context of infectious diseases, particularly in viral infections, as a potential therapeutic target.

Are there any side effects associated with drugs that target PPIA?

Some drugs targeting PPIA may have side effects, including immunosuppression, which needs to be carefully managed.

Is PPIA used in organ transplantation procedures?

Yes, PPIA has been studied in the context of organ transplantation due to its role in immune responses and immunosuppression.

Can PPIA be used as a potential drug target for neuroprotective therapies?

PPIA modulation has shown promise in neuroprotection, making it a potential drug target for neurodegenerative disorders.

Are there any drugs that target PPIA for clinical use?

Some drugs, such as cyclosporine, target PPIA for immunosuppressive purposes in transplantation and autoimmune diseases.