Recombinant Human PPIB Protein (Tyr47-Glu216), His tagged

• Cat.No.: PPIB-5946H
• Product Overview: Recombinant human PPIB (Tyr47-Glu216) fused with His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Tyr47-Glu216
• Description: PPIB is identified as a candidate gene for OI-IX.Osteogenesis imperfecta (OI) is an inherited disorder of connective tissue typically caused by defects in either COL1A1 or COL1A2. A number of other genes causative of this disorder have been found, including PPIB, which forms one subunit of the prolyl 3-hydroxylase enzyme complex.Patients with OI caused by PPIB mutation should have appropriate early and regular management of their hearing.
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 19.84 kDa
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: PPIB peptidylprolyl isomerase B (cyclophilin B) [ Homo sapiens (human) ]
• Official Symbol: PPIB
• Synonyms: PPIB; peptidylprolyl isomerase B (cyclophilin B); peptidyl-prolyl cis-trans isomerase B; CYPB; OI9; PPIase B; rotamase B; S-cyclophilin; cyclophilin-like protein; SCYLP; CYP-S1; MGC2224; MGC14109
• Gene ID: 5479
• mRNA Refseq: NM_000942
• Protein Refseq: NP_000933
• MIM: 123841
• UniProt ID: P23284