Recombinant Human PPP1R16A Protein, MYC/DDK-tagged


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Recombinant Human PPP1R16A Protein, MYC/DDK-tagged

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Cat.No. : PPP1R16A-2750H
Product Overview : Recombinant Human PPP1R16A protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
Description : Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains, which is crucial for muscle and intracellular movement. MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit, a myosin phosphatase targeting (MYPT) subunit, and another smaller subunit. The protein encoded by this gene represents an MYPT subunit, which is responsible for directing PP1c to its intended targets. However, while other MYPTs result in PP1c activation after becoming phosphorylated, the encoded protein is phosphorylated by protein kinase A and then inhibits the catalytic activity of PP1c.
Source : HEK293
Species : Human
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 57.6 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : PPP1R16A protein phosphatase 1, regulatory subunit 16A [ Homo sapiens ]
Official Symbol : PPP1R16A
Synonyms : MYPT3; MYPT3
Gene ID : 84988
mRNA Refseq : NM_032902
Protein Refseq : NP_116291
MIM : 609172
UniProt ID : Q96I34

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