Recombinant Human PPP1R3C Protein, His-tagged

• Cat.No.: PPP1R3C-2619H
• Product Overview: Recombinant Human PPP1R3C Protein (Met1-Arg317) with a N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 40.1 kDa
  Accurate Molecular Mass: 40 kDa
• Protein length: Met1-Arg317
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: PPP1R3C protein phosphatase 1, regulatory subunit 3C [ Homo sapiens (human) ]
• Official Symbol: PPP1R3C
• Synonyms: PPP1R3C; protein phosphatase 1, regulatory subunit 3C; PPP1R5, protein phosphatase 1, regulatory (inhibitor) subunit 3C; protein phosphatase 1 regulatory subunit 3C; Phosphatase 1; regulatory inhibitor subunit 5; protein targeting to glycogen; PTG; PP1 subunit R5; protein phosphatase 1 regulatory subunit 5; Phosphatase 1, regulatory inhibitor subunit 5; protein phosphatase 1, regulatory (inhibitor) subunit 3C; PPP1R5
• Gene ID: 5507
• mRNA Refseq: NM_005398
• Protein Refseq: NP_005389
• MIM: 602999
• UniProt ID: Q9UQK1