| Description : |
The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha). |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
74 kDa |
| AA Sequence : |
MAHHLPAAMENHQDFRSIKAKFQAS QPEPSDLPKKPPKPEFGKLKKFSQP ELSEHPKKAPLPEFGAVSLKPPPPE VTDLPKKPPPPEVTDLPKKPPPPEV TDLPKKPPPPEVTDLPKKPSKLELS DLSKKFPQLGATPFPRKPLQPEVGE APLKASLPEPGAPARKPLQPDELSH PARPPSEPKSGAFPRKLWQPEAGEA TPRSPQPELSTFPKKPAQPEFNVYP KKPPQPQVGGLPKKSVPQPEFSEAA QTPLWKPQSSEPKRDSSAFPKKASQ PPLSDFPKKPPQPELGDLTRTSSEP EVSVLPKRPRPAEFKALSKKPPQPE LGGLPRTSSEPEFNSLPRKLLQPER RGPPRKFSQPEPSAVLKRHPQPEFF GDLPRKPPLPSSASESSLPAAVAGF SSRHPLSPGFGAAGTPRWRSGGLVH SGGARPGLRPSHPPRRRPLPPASSL GHPPAKPPLPPGPVDMQSFRRPSAA SIDLRRTRSAAGLHFQDRQPEDIPQ VPDEIYELYDDVEPRDDSSPSPKGR DEAPSVQQAARRPPQDPALRKEKDP QPQQLPPMDPKLLKQLRKAEKAERE FRKKFKFEGEIVVHTKMMIDPNAKT RRGGGKHLGIRRGEILEVIEFTSNE EMLCRDPKGKYGYVPRTALLPLETE VYDDVDFCDPLENQPLPLGRTRTRP LEQKLISEEDLAANDILDYKDDDDK V |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
