Recombinant Human PREB Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PREB-520H
• Product Overview: PREB MS Standard C13 and N15-labeled recombinant protein (NP_037520) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 45.5 kDa
• AA Sequence: MGRRRAPELYRAPFPLYALQVDPST GLLIAAGGGGAAKTGIKNGVHFLQL ELINGRLSASLLHSHDTETRATMNL ALAGDILAAGQDAHCQLLRFQAHQQ QGNKAEKAGSKEQGPRQRKGAAPAE KKCGAETQHEGLELRVENLQAVQTD FSSDPLQKVVCFNHDNTLLATGGTD GYVRVWKVPSLEKVLEFKAHEGEIE DLALGPDGKLVTVGRDLKASVWQKD QLVTQLHWQENGPTFSSTPYRYQAC RFGQVPDQPAGLRLFTVQIPHKRLR QPPPCYLTAWDGSNFLPLRTKSCGH EVVSCLDVSESGTFLGLGTVTGSVA IYIAFSLQCLYYVREAHGIVVTDVA FLPEKGRGPELLGSHETALFSVAVD SRCQLHLLPSRRSVPVWLLLLLCVG LIIVTILLLQSAFPGFLTRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PREB prolactin regulatory element binding [ Homo sapiens (human) ]
• Official Symbol: PREB
• Synonyms: PREB; prolactin regulatory element binding; prolactin regulatory element-binding protein; SEC12; prolactin regulatory binding-element protein; mammalian guanine nucleotide exchange factor mSec12; MGC3467
• Gene ID: 10113
• mRNA Refseq: NM_013388
• Protein Refseq: NP_037520
• MIM: 606395
• UniProt ID: Q9HCU5