Recombinant Human PRKAB2 Protein (Lys17-Lys260), His tagged

Species :	Human
Source :	E.coli
Tag :	His
Protein Length :	Lys17-Lys260
Description :	Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
Form :	Lyophilized powder/frozen liquid
Molecular Mass :	27.93 kDa
Purity :	> 90 % as determined by SDS-PAGE
Notes :	For research use only.
Storage :	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
Storage Buffer :	Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
Reconstitution :	Reconstitute in sterile water for a stock solution.
Shipping :	They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Name	PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit [ Homo sapiens (human) ]
Official Symbol	PRKAB2
Synonyms	PRKAB2; protein kinase, AMP-activated, beta 2 non-catalytic subunit; 5-AMP-activated protein kinase subunit beta-2; AMPK beta 2; AMPK beta-2 chain; AMPK subunit beta-2; 5-AMP-activated protein kinase, beta-2 subunit; MGC61468;
Gene ID	5565
mRNA Refseq	NM_005399
Protein Refseq	NP_005390
MIM	602741
UniProt ID	O43741