Recombinant Human Protein Arginine Methyltransferase 3, GST-tagged PRMT3-1617H

Recombinant Human Protein Arginine Methyltransferase 3, GST-tagged

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Recombinant Human Protein Arginine Methyltransferase 3, GST-tagged

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Cat.No. : PRMT3-1617H Optional Service: Optional requirements on this protein
Product Overview : Recombinant full-length human PRMT3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description : PRMT3 is a protein arginine methyltransferase that catalyze the formation of asymmetric N (G),N (G)-dimethylarginine (ADMA) residues in proteins. 40S ribosomal protein S2 is a physiological substrate of PRMT3 and PRMT3 regulates ribosome biosynthesis at a stage beyond pre-rRNA processing. DAL-1 (differentially expressed in adenocarcinoma of the lung)/4.1B is a tumor suppressor gene that can significantly inhibits PRMT3 methylation of cellular substrates. Modulation of post-translational methylation may be an important mechanism through which DAL-1/4.1B affects tumor cell growth.
Applications : Western Blot
Molecular Weight : 97 kDa
Expression System : Sf9 insect cells using baculovirus
Species : Human
Form : Recombinant protein stored in 50 mM Tris-HCL, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol, 0.1 mM EDTA.
Purity : > 90 %
Concentration : 0.1 ug/ul
Storage : Store product at -70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
PDBrendering based on 1f3l. :

Gene Name : PRMT3 protein arginine methyltransferase 3 [ Homo sapiens ]
Official Symbol : PRMT3
Synonyms : PRMT3; protein arginine methyltransferase 3; HRMT1L3; HMT1 hnRNP methyltransferase-like 3 (S. cerevisiae); Protein arginine N-methyltransferase 3; EC 2.1.1;Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3
Gene ID : 10196
mRNA Refseq : NM_001145166
Protein Refseq : NP_001138638
MIM : 603190
UniProt ID : O60678
Chromosome Location : 11p15.1
Function : metal ion binding; protein-arginine N-methyltransferase activity; transferase activity; zinc ion binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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