Recombinant Human PSMA1, T7-tagged

• Cat.No.: PSMA1-839H
• Product Overview: Recombinant Human PSMA1 was produced in E.coli with a T7 tag at N-terminus. MW = 29556Da (1-263 aa).

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Protein Length: 1-263 a.a.
• Description: Proteasome subunit alpha type-1 is a protein that in humans is encoded by the PSMA1 gene. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.
• Form: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3. 10mM DTT.
• Purity: 90%.
• Clonality: N/A.
• Applications: MS. SDS.

Gene Information

• Gene Name: PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 [ Homo sapiens ]
• Synonyms: PSMA1; proteasome (prosome, macropain) subunit, alpha type, 1; NU; HC2; PROS30; MGC1667; MGC14542; MGC14575; MGC14751; MGC21459; MGC22853; MGC23915; proteasome subunit alpha type-1; PROS-30; protein P30-33K; proteasome nu chain; macropain subunit C2; macropain subunit nu; proteasome subunit nu; 30 kDa prosomal protein; proteasome component C2; proteasome subunit, alpha-type, 1; multicatalytic endopeptidase complex subunit C2; EC 3.4.25.1
• Gene ID: 5682
• mRNA Refseq: NM_001143937
• Protein Refseq: NP_001137409
• MIM: 602854
• UniProt ID: P25786
• Chromosome Location: 11p15.1
• Pathway: Proteasome
• Function: RNA binding; peptidase activity; protein binding; threonine-type endopeptidase activity