Gene Name |
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 [ Homo sapiens ] |
Official Symbol |
PSMA6 |
Synonyms |
PSMA6; proteasome (prosome, macropain) subunit, alpha type, 6; proteasome subunit alpha type-6; IOTA; MGC2333; MGC22756; MGC23846; p27K; PROS27; PROS-27; macropain iota chain; prosomal P27K protein; proteasome iota chain; macropain subunit iota; 27 kDa prosomal protein; proteasome subunit iota; multicatalytic endopeptidase complex iota chain; |
Gene ID |
5687 |
mRNA Refseq |
NM_002791 |
Protein Refseq |
NP_002782 |
MIM |
602855 |
UniProt ID |
P60900 |
Chromosome Location |
14q13 |
Pathway |
APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; Activation of NF-kappaB in B Cells, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; |
Function |
NF-kappaB binding; RNA binding; RNA binding; endopeptidase activity; peptidase activity; protein binding; purine ribonucleoside triphosphate binding; threonine-type endopeptidase activity; |