Recombinant Human PSMB6 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PSMB6-2657H
• Product Overview: PSMB6 MS Standard C13 and N15-labeled recombinant protein (NP_002789) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 25.4 kDa
• AA Sequence: MAATLLAARGAGPAPAWGPEAFTPD WESREVSTGTTIMAVQFDGGVVLGA DSRTTTGSYIANRVTDKLTPIHDRI FCCRSGSAADTQAVADAVTYQLGFH SIELNEPPLVHTAASLFKEMCYRYR EDLMAGIIIAGWDPQEGGQVYSVPM GGMMVRQSFAIGGSGSSYIYGYVDA TYREGMTKEECLQFTANALALAMER DGSSGGVIRLAAIAESGVERQVLLG DQIPKFAVATLPPATRTRPLEQKLI SEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PSMB6 proteasome 20S subunit beta 6 [ Homo sapiens (human) ]
• Official Symbol: PSMB6
• Synonyms: PSMB6; proteasome (prosome, macropain) subunit, beta type, 6; proteasome subunit beta type-6; DELTA; Y; proteasome subunit Y; macropain delta chain; proteasome delta chain; proteasome subunit delta; proteasome subunit beta 6; proteasome catalytic subunit 1; PSY large multifunctional protease Y; multicatalytic endopeptidase complex delta chain; LMPY; MGC5169
• Gene ID: 5694
• mRNA Refseq: NM_002798
• Protein Refseq: NP_002789
• MIM: 600307
• UniProt ID: P28072