Recombinant Human PSPC1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human PSPC1 Protein, Myc/DDK-tagged, C13 and N15-labeled

PSPC1 Related Products

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Cat.No. : PSPC1-6042H
Product Overview : PSPC1 MS Standard C13 and N15-labeled recombinant protein (NP_001035879) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism. The protein encoded by this gene is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has been identified.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 58.6 kDa
AA Sequence : MMLRGNLKQV RIEKNPARLR ALESAVGESE PAAAAAMALA LAGEPAPPAP APPEDHPDEE MGFTIDIKSF LKPGEKTYTQ RCRLFVGNLP TDITEEDFKR LFERYGEPSE VFINRDRGFG FIRLESRTLA EIAKAELDGT ILKSRPLRIR FATHGAALTV KNLSPVVSNE LLEQAFSQFG PVEKAVVVVD DRGRATGKGF VEFAAKPPAR KALERCGDGA FLLTTTPRPV IVEPMEQFDD EDGLPEKLMQ KTQQYHKERE QPPRFAQPGT FEFEYASRWK ALDEMEKQQR EQVDRNIREA KEKLEAEMEA ARHEHQLMLM RQDLMRRQEE LRRLEELRNQ ELQKRKQIQL RHEEEHRRRE EEMIRHREQE ELRRQQEGFK PNYMENREQE MRMGDMGPRG AINMGDAFSP APAGNQGPPP MMGMNMNNRA TIPGPPMGPG PAMGPEGAAN MGTPMMPDNG AVHNDRFPQG PPSQMGSPMG SRTGSETPQA PMSGVGPVSG GPGGFGRGSQ GGNFEGPNKR RRYTRTRPLE QKLISEEDLA ANDILDYKDD DDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : PSPC1 paraspeckle component 1 [ Homo sapiens (human) ]
Official Symbol : PSPC1
Synonyms : PSPC1; paraspeckle component 1; FLJ10955; PSP1; paraspeckle protein 1; FLJ33554; DKFZp566B1447;
Gene ID : 55269
mRNA Refseq : NM_001042414
Protein Refseq : NP_001035879
MIM : 612408
UniProt ID : Q8WXF1

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