Recombinant Human PTGDS Protein, GST-tagged


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Recombinant Human PTGDS Protein, GST-tagged

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Cat.No. : PTGDS-54H
Product Overview : Recombinant human PTGDS protein with a N-terminal GST-tag was expressed in E. coli.
Description : The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.
Source : E. coli
Species : Human
Tag : GST
Molecular Mass : 46 kDa
Purity : ≥85% estimated by SDS-PAGE
Stability : ≥ 2 years
Storage : Store it at -80 centigrade
Storage Buffer : 50 mM sodium phosphate, pH 7.2, containing 20% glycerol, 150 mM sodium chloride, 1 mM DTT, and 0.5 mM EDTA
SDS-PAGE Analysis of PTGDS :

Lane 1: MW Markers; Lane 2: Prostaglandin D Synthase (lipocalin-type; human recombinant) (2 μg); Lane 3: Prostaglandin D Synthase (lipocalin-type; human recombinant) (4 μg). Representative gel image shown; actual purity may vary between each batch.

Gene Name : PTGDS prostaglandin D2 synthase [ Homo sapiens (human) ]
Official Symbol : PTGDS
Synonyms : PTGDS; prostaglandin D2 synthase; PDS; PGD2; PGDS; LPGDS; PGDS2; L-PGDS; prostaglandin-H2 D-isomerase; PGD2 synthase; beta-trace protein; cerebrin-28; glutathione-independent PGD synthase; glutathione-independent PGD synthetase; lipocalin-type prostaglandin D synthase; prostaglandin D synthase; prostaglandin D2 synthase 21kDa (brain); testis tissue sperm-binding protein Li 63n
Gene ID : 5730
mRNA Refseq : NM_000954
Protein Refseq : NP_000945
MIM : 176803
UniProt ID : P41222
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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