Recombinant Human PTGDS Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PTGDS-993H
• Product Overview: PTGDS MS Standard C13 and N15-labeled recombinant protein (NP_000945) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 20.8 kDa
• AA Sequence: MATHHTLWMGLALLGVLGDLQAAPE AQVSVQPNFQQDKFLGRWFSAGLAS NSSWLREKKAALSMCKSVVAPATDG GLNLTSTFLRKNQCETRTMLLQPAG SLGSYSYRSPHWGSTYSVSVVETDY DQYALLYSQGSKGPGEDFRMATLYS RTQTPRAELKEKFTAFCKAQGFTED TIVFLPQTDKCMTEQTRTRPLEQKL ISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PTGDS prostaglandin D2 synthase [ Homo sapiens (human) ]
• Official Symbol: PTGDS
• Synonyms: PTGDS; prostaglandin D2 synthase 21kDa (brain); prostaglandin D2 synthase (21kD, brain); prostaglandin-H2 D-isomerase; L PGDS; lipocalin type prostaglandin D synthase; PGDS; cerebrin-28; PGD2 synthase; beta-trace protein; prostaglandin D synthase; prostaglandin-D2 synthase; glutathione-independent PGD synthase; glutathione-independent PGD synthetase; lipocalin-type prostaglandin D synthase; lipocalin-type prostaglandin-D synthase; PDS; PGD2; LPGDS; PGDS2; L-PGDS
• Gene ID: 5730
• mRNA Refseq: NM_000954
• Protein Refseq: NP_000945
• MIM: 176803
• UniProt ID: P41222