Recombinant Human PTHLH Protein, His tagged

• Cat.No.: PTHLH-322H
• Product Overview: Recombinant Human PTHLH Protein (25-177 aa) with His tag was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: 25-177 aa
• Description: The protein encoded by this gene is a member of the parathyroid hormone family. This hormone, via its receptor, PTHR1, regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. It is responsible for most cases of humoral hypercalcemia of malignancy, and mutations in this gene are associated with brachydactyly type E2 (BDE2). Alternatively spliced transcript variants have been found for this gene. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, downstream of the initiator AUG codon, resulting in nuclear forms of this hormone.
• Molecular Mass: 19 kDa
• AA Sequence: RSVEGLSRRLKRAVSEHQLLHDKGKSIQDLRRRFFLHHLIAEIHTAEIRATSEVSPNSKPSPNTKNHPVRFGSDDEGRYLTQETNKVETYKEQPLKTPGKKKKGKPGKRKEQEKKKRRTRSAWLDSGVTGSGLEGDHLSDTSTTSLELDSRRHHHHHHHHHHH
• Biotin binding Site: 0
• Endotoxin: <1.0 EU/μg of the protein by the LAL method.
• Purity: > 80% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Sterile PBS, pH 7.4
• Concentration: 0.1 mg/mL by BCA

Gene Information

• Gene Name: PTHLH parathyroid hormone-like hormone [ Homo sapiens (human) ]
• Official Symbol: PTHLH
• Synonyms: PTHLH; parathyroid hormone-like hormone; parathyroid hormone-related protein; HHM; osteostatin; PLP; PTHR; PTHRP; PTH-rP; PTH-related protein; parathyroid hormone-like related protein; BDE2; MGC14611
• Gene ID: 5744
• mRNA Refseq: NM_002820
• Protein Refseq: NP_002811
• MIM: 168470
• UniProt ID: P12272