Recombinant Human PTP4A2(2-167), His-tagged
Cat.No. : | PTP4A2-505H |
Product Overview : | Recombinant human PTP4A2 protein(2-167) with N-terminal His tag was expressed in anE.coliexpression system, MW= 19.1 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PTP4A2-505H |
Description : | Protein tyrosine phosphatase type IVA 2 is an enzyme that in humans is encoded by the PTP4A2 gene. he protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. |
Source : | E.coli. |
Purity : | > 90%. |
Formulation : | 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 20% glycerol, and 3 mM DTT. |
Specific Activity : | 0.334 pmol/min/μg, Assay conditions: enzyme was incubated in50mM Tris pH7.4, 150mM NaCl 5mM DTT, and 12.5mM PNPP as a substrate for 2h at 37°C. Absorbance was read by Tecan spectraphotometer at 405 nm wavelength. |
Application : | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Storage : | >6 months at –80°C. |
Gene Name : | PTP4A2 protein tyrosine phosphatase type IVA, member 2 [ Homo sapiens ] |
Synonyms : | PTP4A2; protein tyrosine phosphatase type IVA, member 2; HH13; OV-1; PRL2; HH7-2; PRL-2; PTP4A; HU-PP-1; PTPCAAX2; ptp-IV1a; ptp-IV1b; Protein tyrosine phosphatase type IVA 2; EC 3.1.3.48; Protein-tyrosine phosphatase 4a2; BM-008; Protein-tyrosine phosphatase of regenerating liver 2 |
Gene ID : | 8073 |
mRNA Refseq : | NM_080391 |
Protein Refseq : | NP_536316 |
MIM : | 601584 |
UniProt ID : | Q12974 |
Chromosome Location : | 1p35 |
Function : | prenylated protein tyrosine phosphatase activity; hydrolase activity; protein binding |
Products Types
◆ Recombinant Protein | ||
PTP4A2-3944H | Recombinant Human PTP4A2 Protein, His (Fc)-Avi-tagged | +Inquiry |
PTP4A2-2546H | Recombinant Human PTP4A2 protein(Asn2-Gln167), GST-tagged | +Inquiry |
PTP4A2-3515R | Recombinant Rhesus Macaque PTP4A2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ptp4a2-5231M | Recombinant Mouse Ptp4a2 Protein, Myc/DDK-tagged | +Inquiry |
PTP4A2-4487R | Recombinant Rat PTP4A2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PTP4A2-2694HCL | Recombinant Human PTP4A2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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