Recombinant Human PTPRD protein, His-tagged

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Recombinant Human PTPRD protein, His-tagged

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Cat.No. : PTPRD-36H
Product Overview : Recombinant Human PTPRD protein (Glu21-Glu1265), fused to His tag at C-terminus, was expressed in human 293 cells (HEK293).
Description : Receptor-type tyrosine-protein phosphatase delta is an enzyme that is encoded by the PTPRD gene. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPRD has been shown to interact with PTPRS and liprin-alpha-1. Studies of the similar genes in chick and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple tissue specific alternatively spliced transcript variants of this gene have been reported. Mutations in the PTPRD gene are associated with autism, obsessive–compulsive disorder, and breast cancer.
Source : HEK293
Species : Human
Tag : His
Form : Lyophilized from 0.22 um filtered solution in PBS, pH7.4, 10% trehalose.
Molecular Mass : The protein has a calculated MW of 140 kDa. The protein migrates as 19 kDa and 120-130 kDa under reducing (R) condition (SDS-PAGE).
Protein length : 1245
Endotoxin : Less than 1.0 EU per ug by the LAL method.
Purity : >90% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 centigrade to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
SDS-PAGE of PTPRD-36H :

Human PTPRD, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

Gene Name : PTPRD
Official Symbol : PTPRD
Synonyms : PTPRD; protein tyrosine phosphatase, receptor type, D; receptor-type tyrosine-protein phosphatase delta; HPTP; PTPD; R-PTP-delta; protein-tyrosine phosphatase delta; protein tyrosine phosphatase, receptor type, delta polypeptide; HPTPD; HPTPDELTA; RPTPDELTA; MGC119750; MGC119751; MGC119752; MGC119753
Gene ID : 5789
mRNA Refseq : NM_001040712
Protein Refseq : NP_001035802
MIM : 601598
UniProt ID : P23468
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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