Recombinant Human PYGL Protein (2-846 aa), GST-tagged

• Cat.No.: PYGL-759H
• Product Overview: Recombinant Human PYGL Protein (2-846 aa) is produced by E. coli expression system. This protein is fused with a GST tag at the N-terminal. Research Area: Metabolism. Protein Description: Partial.

Specification

• Description: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
• Source: E. coli
• Species: Human
• Tag: GST
• Form: Tris-based buffer, 50% glycerol
• Molecular Mass: 123.9 kDa
• Protein length: 2-846 aa
• AA Sequence: AKPLTDQEKRRQISIRGIVGVENVA ELKKSFNRHLHFTLVKDRNVATTRD YYFALAHTVRDHLVGRWIRTQQHYY DKCPKRVYYLSLEFYMGRTLQNTMI NLGLQNACDEAIYQLGLDIEELEEI EEDAGLGNGGLGRLAACFLDSMATL GLAAYGYGIRYEYGIFNQKIRDGWQ VEEADDWLRYGNPWEKSRPEFMLPV HFYGKVEHTNTGTKWIDTQVVLALP YDTPVPGYMNNTVNTMRLWSARAPN DFNLRDFNVGDYIQAVLDRNLAENI SRVLYPNDNFFEGKELRLKQEYFVV AATLQDIIRRFKASKFGSTRGAGTV FDAFPDQVAIQLNDTHPALAIPELM RIFVDIEKLPWSKAWELTQKTFAYT NHTVLPEALERWPVDLVEKLLPRHL EIIYEINQKHLDRIVALFPKDVDRL RRMSLIEEEGSKRINMAHLCIVGSH AVNGVAKIHSDIVKTKVFKDFSELE PDKFQNKTNGITPRRWLLLCNPGLA ELIAEKIGEDYVKDLSQLTKLHSFL GDDVFLRELAKVKQENKLKFSQFLE TEYKVKINPSSMFDVQVKRIHEYKR QLLNCLHVITMYNRIKKDPKKLFVP RTVIIGGKAAPGYHMAKMIIKLITS VADVVNNDPMVGSKLKVIFLENYRV SLAEKVIPATDLSEQISTAGTEASG TGNMKFMLNGALTIGTMDGANVEMA EEAGEENLFIFGMRIDDVAALDKKG YEAKEYYEALPELKLVIDQIDNGFF SPKQPDLFKDIINMLFYHDRFKVFA DYEAYVKCQDKVSQLYMNPKAWNTM VLKNIAASGKFSSDRTIKEYAQNIW NVEPSDLKISLSNESNKVNG
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with concentration instruction is sent along with the products.

Gene Information

• Gene Name: PYGL phosphorylase, glycogen, liver [ Homo sapiens ]
• Official Symbol: PYGL
• Synonyms: PYGL; liver; Hers disease; GSD6
• Gene ID: 5836
• mRNA Refseq: NM_001163940
• Protein Refseq: NP_001157412
• MIM: 613741
• UniProt ID: P06737