Recombinant Human RAB17, His-tagged

• Cat.No.: RAB17-3588H
• Product Overview: Recombinant human RAB17 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography (1-212aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: RAB17, also known as Ras-related protein Rab17, belongs to the small GTPase superfamily, Rab GTPases are localized to various intracellular compartments and are known to play important regulatory roles in membrane trafficking. It is regulated traffic through the apical recycling endosome, suggested function in polarized sorting in epithelial cells.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 30% glycerol, 0.1M NaCl,1mM DTT
• Molecular Weight: 25.6 kDa(232aa), confirmed by MALDI-TOF
• Purity: > 90% by SDS - PAGE
• Concentration: 0.5 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MAQAHRTPQP RAAPSQPRVF KLVLLGSGSV GKSSLALRYV KNDFKSILPT VGCAFFTKVV DVGATSLKLE IWDTAGQEKY HSVCHLYFRG ANAALLVYDI TRKDSFLKAQ QWLKDLEEEL HPGEVLVMLV GNKTDLSQER EVTFQEGKEF ADSQKLLFME TSAKLNHQVS EVFNTVAQEL LQRSDEEGQA LRGDAAVALN KGPARQAKCC AH
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: RAB17 RAB17, member RAS oncogene family [ Homo sapiens ]
• Official Symbol: RAB17
• Synonyms: RAB17; RAB17, member RAS oncogene family; ras-related protein Rab-17; Ras-related protein Rab-17; OTTHUMP00000164417; OTTHUMP00000202805; FLJ12538
• Gene ID: 64284
• mRNA Refseq: NM_022449
• Protein Refseq: NP_071894
• MIM: 602206
• UniProt ID: Q9H0T7
• Chromosome Location: 2q37.3
• Function: GTP binding; nucleotide binding; protein binding