Recombinant Human RAB18, Member RAS Oncogene Family, His-tagged

• Cat.No.: RAB18-1289H
• Product Overview: Recombinant human Rab18 protein, fused to T7-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: RAB18 is a member of a family of Ras-related small GTPase that is lipid-anchored to the cytoplasmic side of the cell membrane. It plays a role in apical recycling and endocytosis and is also thought to be involved in protein transport between early endosomes and the plasma membrane.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 7.5) containing 1mM DTT.
• Molecular Weight: 24.5 kDa (221aa)
• Purity: > 90 % by SDS - PAGE
• Concentration: 1 mg/ml (determined by Bradford)
• Sequences of amino acids: MASMTGGQQM GRGSHMDEDV LTTLKILIIG ESGVGKSSLL LRFTDDTFDP ELAATIGVDF KVKTISVDGN KAKLAIWDTA GQERFRTLTP SYYRGAQGVI LVYDVTRRDT FVKLDNWLNE LETYCTRNDI VNMLVGNKID KENREVDRNE GLKFARKHSM LFIEASAKTC DGVQCAFEEL VEKIIQTPGL WESENQNKGV KLSHREEGQG GGACGGYCSV L
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: RAB18 RAB18, member RAS oncogene family [ Homo sapiens ]
• Official Symbol: RAB18
• Synonyms: RAB18; RAB18, member RAS oncogene family; RAB18LI1; ras-related protein Rab-18; OTTHUMP00000019371; OTTHUMP00000019372; OTTHUMP00000019373; RAB18 small GTPase; Ras-related protein Rab-18
• Gene ID: 22931
• mRNA Refseq: NM_021252
• Protein Refseq: NP_067075
• MIM: 602207
• UniProt ID: Q9NP72
• Chromosome Location: 10p12.1
• Function: ATP binding;GTP binding;GTPase activity; nucleotide binding;transcription factor binding