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Recombinant Human RABGEF1 Protein (1-491 aa), His-SUMO-tagged

Cat.No. : RABGEF1-1149H
Product Overview : Recombinant Human RABGEF1 Protein (1-491 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Signal Transduction. Protein Description: Full Length of Isoform 2.
  • Specification
  • Gene Information
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Description : Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic mbrane fusion and mbrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase.
Source : E. coli
Species : Human
Tag : His-SUMO
Form : Tris-based buffer, 50% glycerol
Molecular Mass : 72.9 kDa
Protein length : 1-491 aa
AA Sequence : MSLKSERRGIHVDQSDLLCKKGCGY YGNPAWQGFCSKCWREEYHKARQKQ IQEDWELAERLQREEEEAFASSQSS QGAQSLTFSKFEEKKTNEKTRKVTT VKKFFSASSRVGSKKEIQEAKAPSP SINRQTSIETDRVSKEFIEFLKTFH KTGQEIYKQTKLFLEGMHYKRDLSI EEQSECAQDFYHNVAERMQTRGKVP PERVEKIMDQIEKYIMTRLYKYVFC PETTDDEKKDLAIQKRIRALRWVTP QMLCVPVNEDIPEVSDMVVKAITDI IEMDSKRVPRDKLACITKCSKHIFN AIKITKNEPASADDFLPTLIYIVLK GNPPRLQSNIQYITRFCNPSRLMTG EDGYYFTNLCCAVAFIEKLDAQSLN LSQEDFDRYMSGQTSPRKQEAESWS PDACLGVKQMYKNLDLLSQLNERQE RIMNEAKKLEKDLIDWTDGIAREVQ DIVEKYPLEIKPPNQPLAAIDSENV ENDKLPPPLQPQVYAG
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with concentration instruction is sent along with the products.
Gene Name : RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 [ Homo sapiens ]
Official Symbol : RABGEF1
Synonyms : RABGEF1; rabex 5; RABEX5; RAP1; rabex-5; FLJ32302;
Gene ID : 27342
mRNA Refseq : NM_014504
Protein Refseq : NP_055319
MIM : 609700
UniProt ID : Q9UJ41

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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