Recombinant Human RABGEF1 Protein (1-491 aa), His-SUMO-tagged
| Cat.No. : | RABGEF1-1149H |
| Product Overview : | Recombinant Human RABGEF1 Protein (1-491 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Signal Transduction. Protein Description: Full Length of Isoform 2. |
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| Species : | Human |
| Source : | E.coli |
| Tag : | His&SUMO |
| Protein Length : | 1-491 aa |
| Description : | Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic mbrane fusion and mbrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase. |
| Form : | Tris-based buffer, 50% glycerol |
| Molecular Mass : | 72.9 kDa |
| AA Sequence : | MSLKSERRGIHVDQSDLLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEGMHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKKDLAIQKRIRALRWVTPQMLCVPVNEDIPEVSDMVVKAITDIIEMDSKRVPRDKLACITKCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPDACLGVKQMYKNLDLLSQLNERQERIMNEAKKLEKDLIDWTDGIAREVQDIVEKYPLEIKPPNQPLAAIDSENVENDKLPPPLQPQVYAG |
| Purity : | > 90% as determined by SDS-PAGE. |
| Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration : | A hardcopy of COA with concentration instruction is sent along with the products. |
| Gene Name | RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 [ Homo sapiens ] |
| Official Symbol | RABGEF1 |
| Synonyms | RABGEF1; rabex 5; RABEX5; RAP1; rabex-5; FLJ32302; |
| Gene ID | 27342 |
| mRNA Refseq | NM_014504 |
| Protein Refseq | NP_055319 |
| MIM | 609700 |
| UniProt ID | Q9UJ41 |
Not For Human Consumption!
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