Recombinant Human RAD1 Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: RAD1-331H
• Product Overview: RAD1 MS Standard C13 and N15-labeled recombinant protein (NP_002844) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jan 2009]
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 31.8 kDa
• AA Sequence: MPLLTQQIQDEDDQYSLVASLDNVR NLSTILKAIHFREHATCFATKNGIK VTVENAKCVQANAFIQAGIFQEFKV QEESVTFRINLTVLLDCLSIFGSSP MPGTLTALRMCYQGYGYPLMLFLEE GGVVTVCKINTQEPEETLDFDFCST NVINKIILQSEGLREAFSELDMTSE VLQITMSPDKPYFRLSTFGNAGSSH LDYPKDSDLMEAFHCNQTQVNRYKI SLLKPSTKALVLSCKVSIRTDNRGF LSLQYMIRNEDGQICFVEYYCCPDE EVPESESTRTRPLEQKLISEEDLAA NDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RAD1 RAD1 homolog (S. pombe) [ Homo sapiens (human) ]
• Official Symbol: RAD1
• Synonyms: RAD1; RAD1 homolog (S. pombe); RAD1 (S. pombe) homolog; cell cycle checkpoint protein RAD1; cell cycle checkpoint protein Hrad1; checkpoint control protein HRAD1; DNA repair exonuclease REC1; exonuclease homolog RAD1; HRAD1; Rad1 like DNA damage checkpoint; REC1; DNA repair exonuclease rad1 homolog; rad1-like DNA damage checkpoint protein
• Gene ID: 5810
• mRNA Refseq: NM_002853
• Protein Refseq: NP_002844
• MIM: 603153
• UniProt ID: O60671