Recombinant Human RANGAP1 Protein, His-tagged

• Cat.No.: RANGAP1-12H
• Product Overview: Recombinant Human RANGAP1(418-end) Protein was expressed in E.coli cells using an N-terminal His tag.

Specification

• Description: This gene encodes a protein that associates with the nuclear pore complex and participates in the regulation of nuclear transport. The encoded protein interacts with Ras-related nuclear protein 1 (RAN) and regulates guanosine triphosphate (GTP)-binding and exchange. Alternative splicing results in multiple transcript variants.
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: ~20 kDa
• Purity: The purity of RanGAP1 protein was determined to be ~90% by densitometry.
• Stability: One at -70 centigrade from date of shipment.
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.5 μg/μL
• Storage Buffer: Recominant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0,1mM PMSF, 2mM DTT, and 25% glycerol.

Gene Information

• Gene Name: RANGAP1 Ran GTPase activating protein 1 [ Homo sapiens (human) ]
• Official Symbol: RANGAP1
• Synonyms: RANGAP1; Ran GTPase activating protein 1; SD; Fug1; RANGAP; ran GTPase-activating protein 1; segregation distorter homolog; segregation distortion
• Gene ID: 5905
• mRNA Refseq: NM_002883
• Protein Refseq: NP_002874
• MIM: 602362
• UniProt ID: P46060