Recombinant Human Ras Homolog Gene Family, Member D, His-tagged

• Cat.No.: RHOD-1629H
• Product Overview: Recombinant full length human RHOD was expressed in E. coli cells using an N-terminal His tag.

Specification

• Cat. No.: RHOD-1629H
• Description: RHOD is a member of the Rho gene family that interacts with protein kinases and serves as a target of activated GTPase. RHOD binds GTP and plays a critical role in muscle differentiation by regulating the expression of myogenin and MEF2 genes. Furthermore, RHOD is involved in endosome dynamics and reorganization of the actin cytoskeleton and plays a role in coordinating membrane transport.
• Applications: Kinase Assay; Western Blot
• Molecular Weight: 22 kDa
• Expression System: E. coli
• Species: Human
• Form: Recombinant protein stored in 50 mM MOPS, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25 % glycerol.
• Purity: > 80 %
• Concentration: 0.2 ug/ul
• Sequences: Full length
• Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Pathways: Axon guidance; Rho GTPase cycle; Signaling by Rho GTPases

Gene Information

• Gene Name: RHOD ras homolog gene family, member D [ Homo sapiens ]
• Official Symbol: RHOD
• Synonyms: RHOD; ras homolog gene family, member D; Rho; ARHD; RHOM; RHOHP1; rho-related GTP-binding protein RhoD; ras homolog D; OTTHUMP00000235165; Rho-related protein HP1; ras homolog gene family, member A; Rho-related GTP-binding protein RhoD; Rho-related protein HP1
• Gene ID: 29984
• mRNA Refseq: NM_014578
• Protein Refseq: NP_055393
• MIM: 605781
• UniProt ID: O00212
• Chromosome Location: 11q14.3
• Function: GTP binding; GTPase activity; nucleotide binding