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Recombinant Human RBBP8 Protein, GST-tagged

Cat.No. : RBBP8-2202H
Product Overview : Human RBBP8 full-length ORF ( NP_002885.1, 1 a.a. - 897 a.a.) recombinant protein with GST-tag at N-terminal was expressed in wheat germ.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene.
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 128.3 kDa
AASequence : MNISGSSCGSPNSADTSSDFKDLWT KLKECHDREVQGLQVKVTKLKQERI LDAQRLEEFFTKNQQLREQQKVLHE TIKVLEDRLRAGLCDRCAVTEEHMR KKQQEFENIRQQNLKLITELMNERN TLQEENKKLSEQLQQKIENDQQHQA AELECEEDVIPDSPITAFSFSGVNR LRRKENPHVRYIEQTHTKLEHSVCA NEMRKVSKSSTHPQHNPNENEILVA DTYDQSQSPMAKAHGTSSYTPDKSS FNLATVVAETLGLGVQEESETQGPM SPLGDELYHCLEGNHKKQPFEESTR NTEDSLRFSDSTSKTPPQEELPTRV SSPVFGATSSIKSGLDLNTSLSPSL LQPGKKKHLKTLPFSNTCISRLEKT RSKSEDSALFTHHSLGSEVNKIIIQ SSNKQILINKNISESLGEQNRTEYG KDSNTDKHLEPLKSLGGRTSKRKKT EEESEHEVSCPQASFDKENAFPFPM DNQFSMNGDCVMDKPLDLSDRFSAI QRQEKSQGSETSKNKFRQVTLYEAL KTIPKGFSSSRKASDGNCTLPKDSP GEPCSQECIILQPLNKCSPDNKPSL QIKEENAVFKIPLRPRESLETENVL DDIKSAGSHEPIKIQTRSDHGGCEL ASVLQLNPCRTGKIKSLQNNQDVSF ENIQWSIDPGADLSQYKMDVTVIDT KDGSQSKLGGETVDMDCTLVSETVL LKMKKQEQKGEKSSNEERKMNDSLE DMFDRTTHEEYESCLADSFSQAADE EEELSTATKKLHTHGDKQDKVKQKA FVEPYFKGDERETSLQNFPHIEVVR KKEERRKLLGHTCKECEIYYADMPA EEREKKLASCSRHRFRYIPPNTPEN FWEVGFPSTQTCMERGYIKEDLDPC PRPKRRQPYNAIFSPKGKEQKT
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : RBBP8 RB binding protein 8, endonuclease [ Homo sapiens (human) ]
Official Symbol : RBBP8
Synonyms : RBBP8; RB binding protein 8, endonuclease; RIM; COM1; CTIP; JWDS; SAE2; SCKL2; DNA endonuclease RBBP8; CTBP-interacting protein; RBBP-8; retinoblastoma binding protein 8; sporulation in the absence of SPO11 protein 2 homolog
Gene ID : 5932
mRNA Refseq : NM_002894
Protein Refseq : NP_002885
MIM : 604124
UniProt ID : Q99708

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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