Recombinant Human RCBTB1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: RCBTB1-2406H
• Product Overview: RCBTB1 MS Standard C13 and N15-labeled recombinant protein (NP_060661) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 58.1 kDa
• AA Sequence: MVDVGKWPIFTLLSPQEIASIRKAC VFGTSASEALYVTDNDEVFVFGLNY SNCLGTGDNQSTLVPKKLEGLCGKK IKSLSYGSGPHVLLSTEDGVVYAWG HNGYSQLGNGTTNQGIAPVQVCTNL LIKQVVEVACGSHHSMALAADGEVF AWGYNNCGQVGSGSTANQPTPRKVT NCLHIKRVVGIACGQTSSMAVLDNG EVYGWGYNGNGQLGLGNNGNQLTPV RVAALHSVCVNQIVCGYAHTLALTD EGLLYAWGANTYGQLGTGNKNNLLS PAHIMVEKERVVEIAACHSAHTSAA KTQGGHVYMWGQCRGQSVILPHLTH FSCTDDVFACFATPAVSWRLLSVEH EDFLTVAESLKKEFDSPETADLKFR IDGKYIHVHKAVLKIRCEHFRSMFQ SYWNEDMKEVIEIDQFSYPVYRAFL QYLYTDTVDLPPEDAIGLLDLATSY CENRLKKLCQHIIKRGITVENAFSL FSAAVRYDAEDLEEFCFKFCINHLT EVTQTAAFWQMDGPLLKEFIAKASK CGAFKNTRTRPLEQKLISEEDLAAN DILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RCBTB1 RCC1 and BTB domain containing protein 1 [ Homo sapiens (human) ]
• Official Symbol: RCBTB1
• Synonyms: RCBTB1; regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1; RCC1 and BTB domain-containing protein 1; CLLD7; CLLL7; FLJ10716; CLL deletion region gene 7 protein; GDP/GTP exchange factor (GEF)-like protein; chronic lymphocytic leukemia deletion region gene 7 protein; regulator of chromosome condensation and BTB domain-containing protein 1; GLP; MGC33184; RP11-185C18.1
• Gene ID: 55213
• mRNA Refseq: NM_018191
• Protein Refseq: NP_060661
• MIM: 607867
• UniProt ID: Q8NDN9