| Description : |
The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
71.2 kDa |
| AA Sequence : |
MEAAAAAAAAAAAAAAAGGGCGSGP PPLLLSEGEQQCYSELFARCAGAAG GGPGSGPPEAARVAPGTATAAAGPV ADLFRASQLPAETLHQITELCGAKR VGYFGPTQFYIALKLIAAAQSGLPV RIESIKCELPLPRFMMSKNDGEIRF GNPAELHGTKVQIPYLTTEKNSFKR MDDEDKQETQSPTMSPLASPPSSPP HYQRVPLSHGYSKLRSSAEQMHPAP YEARQPLVQPEGSSSGGPGTKPLRH QASLIRSFSVERELQDNSSYPDEPW RITEEQREYYVNQFRSLQPDPSSFI SGSVAKNFFTKSKLSIPELSYIWEL SDADCDGALTLPEFCAAFHLIVARK NGYPLPEGLPPTLQPEYLQAAFPKP KWDCQLFDSYSESLPANQQPRDLNR MEKTSVKDMADLPVPNQDVTSDDKQ ALKSTINEALPKDVSEDPATPKDSN SLKARPRSRSYSSTSIEEAMKRGED PPTPPPRPQKTHSRASSLDLNKVFQ PSVPATKSGLLPPPPALPPRPCPSQ SEQVSEAELLPQLSRAPSQAAESSP AKKDVLYSQPPSKPIRRKFRPENQA TENQEPSTAASGPASAATMKPHPTV QKQSSKQKKAIQTAIRKNKEANAVL ARLNSELQQQLKEVHQERIALENQL EQLRPVTVLTRTRPLEQKLISEEDL AANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
