Recombinant Human Retinoblastoma Binding Protein 9, His-tagged

• Cat.No.: RBBP9-1543H
• Product Overview: Recombinant human RBBP9 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: Retinoblastoma binding protein, also known as RBBP9, localizes to both the nucleus and the cytoplasm. RBBP9 is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Specifically, RBBP9 interacts with retinoblastoma(Rb) and provides cellular resistance to the growth-inhibitory effects of TGFbeta1, thus facilitating the cellular transformation process.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
• Molecular Weight: 23.1 kDa (206aa), confirmed by MALDI-TOF
• Purity: > 95% by SDS - PAGE
• Concentration: 0.5 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MASPSKAVIV PGNGGGDVTT HGWYGWVKKE LEKIPGFQCL AKNMPDPITA RESIWLPFME TELHCDEKTI IIGHSSGAIA AMRYAETHRV YAIVLVSAYT SDLGDENERA SGYFTRPWQW EKIKANCPYI VQFGSTDDPF LPWKEQQEVA DRLETKLHKF TDCGHFQNTE FHELITVVKS LLKVPA
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: RBBP9 retinoblastoma binding protein 9 [ Homo sapiens ]
• Official Symbol: RBBP9
• Synonyms: RBBP9; BOG; RBBP10; MGC9236; retinoblastoma binding protein 9; putative hydrolase RBBP9; RBBP-9; RBBP-10; OTTHUMP00000030360; retinoma-binding protein 9; B5T overexpressed gene protein; B5T-overexpressed gene protein; retinoblastoma-binding protein 9; retinoblastoma-binding protein 10
• Gene ID: 1074
• mRNA Refseq: NM_006606
• Protein Refseq: NP_006597
• MIM: 602908
• UniProt ID: O75884
• Chromosome Location: 20p11.2
• Function: hydrolase activity